Wufsus et al (2013) [http://dx.doi.org/10.1016/j.bpj.2013.02.055] published a nice investigation of blood clot hydrodynamic permeability dependency on volume fraction of fiber and platelet. Fiber volume fraction was in limits of 0.03, while platelet volume fraction was in limits of 0.01–0.61, what means that that blood clot was enriched by platelets.

However, for a healthy person the platelets occupy approximately only 0.3% of the blood’s volume. Therefore blood clot, formed in the subarachnoid space after aneurysmal rupture, cannot be enriched by platelets and results of Wufsus et al (2013) cannot be applied for estimation of permeability of the blood clot partially diluted by cerebrospinal fluid.

What are porosity and hydrodynamic permeability of pure blood clot and blood clot formed in the subarachnoid space depending on dilution of blood by cerebrospinal fluid?

Thank you very much in advance,

Algis