What are the methods to differentiate clinical and environmental strains(PGPR) of Serratia marcescens? Can environmental strain switch to being an opportunistic pathogen?
It is a citation: "Most genomes from a nosocomial setting and environmental origin could be assigned to the proposed nosocomial or environmental MLSTs, which is indicative of an association between source and genotype. The fact that a few genomes from a nosocomial source showed an environmental MLST suggests that a minority of nosocomial strains have recently derived from the environment..."
Abreo, E., Altier, N. Pangenome of Serratia marcescens strains from nosocomial and environmental origins reveals different populations and the links between them. Sci Rep 9, 46 (2019). https://doi.org/10.1038/s41598-018-37118-0
Dibya Bhatta I would recommend to read a review by Mahlen, Steven D. "Serratia infections: from military experiments to current practice." Clinical microbiology reviews 24.4 (2011): 755-791.