I would like to know the changes in statin prescription rates and cholesterol treatment guidelines over time (i.e. from the introduction of statins until the present time in the United States and Europe). I am especially interested in the context of secondary prevention of embolic stroke. Are you aware of any published data or do you know where I can find out-dated versions of cholesterol treatment guidelines? Thank you for your suggestions.
Look for National Cholesterol Education program, they developed the guidelines for the US. Europe is always following.
OVERTREATMENT.
EH SIDIBE TROPICAL ENDOCRINOLOGIST/POBOX 5062 DAKAR FANN SENEGAL
The trend right now, if I am correct, is the utilization of NCEP ATP guidelines as correctly mentioned by Michael. The British often stratify patients using the Framingham score. Usually a combination of both seems to be the norm in correctly diagnosing dyslipidaemia. Of course, familial dyslipidaemia requires the utilization of the Simon Broome's criteria and is a different story altogether.
Each organissation develops their own clinical guidelines. Depending on your research you should target each country and the national organisation in charge of developing the guidelines. For Spain you can find the information on this website: :http://portal.guiasalud.es/web/guest/guias-practica-clinica. they collect all the different clinical guidelines developed by the different regional governments (17 in Spain), so usually if they exist you can find them on this website, if not I;m afraid that you should contact each autonomous community one by one.
You could contact Guia Salud (through the website)and ask if they keep track of old guidelines.
For European Countries having different regional health governments (Germany, Italy) you will probably face the same problems of non-centralised information.
For UK, they use the guidelines of NECP , ATP III, as mentioned ,through the NIH you can find them easily on their website, the one I found is from 2002 and I also found an 2004 update in an interesting article: http://www.nhlbi.nih.gov/files/docs/guidelines/atp3upd04.pdf ,page 237
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