type 1.5 diabetes is the late onset of autoimmune type 1 diabetes
Type 1.5 diabetes is a non-official term that is sometimes used to refer to a form of type 1 diabetes known as Latent Autoimmune Diabetes in Adults (LADA). The term type 1.5 refers to the fact that the condition is a form of type 1 diabetes that can share some features that are more commonly associated with type 2 diabetes.
Type 1.5 diabetes is sometimes also called as type 3 diabetes or “double diabetes,” because the adult has aspects of both Type 1 and Type 2 diabetes. Type 1.5 diabetics are said to have “double” diabetes because they show both the autoimmune destruction of beta cells of Type 1 diabetes and the insulin resistance characteristic of Type 2 diabetes. People with Type 1.5 have autoantibodies and gradually lose their insulin-producing capability, requiring insulin within 5–10 years of diagnosis. As their insulin resistance suggests, many people with Type 1.5 diabetes are obese or overweight.
Misdiagnosis as having type 2 diabetes is common. Around 15-20% of people diagnosed with type 2 diabetes may actually have Type 1.5 diabetes.
Type 1.5 diabetes is a non-official term that is sometimes used to refer to a form of type 1 diabetes known as Latent Autoimmune Diabetes in Adults (LADA). The term type 1.5 refers to the fact that the condition is a form of type 1 diabetes that can share some features that are more commonly associated with type 2 diabetes.
Type 1.5 diabetes is sometimes also called as type 3 diabetes or “double diabetes,” because the adult has aspects of both Type 1 and Type 2 diabetes. Type 1.5 diabetics are said to have “double” diabetes because they show both the autoimmune destruction of beta cells of Type 1 diabetes and the insulin resistance characteristic of Type 2 diabetes. People with Type 1.5 have autoantibodies and gradually lose their insulin-producing capability, requiring insulin within 5–10 years of diagnosis. As their insulin resistance suggests, many people with Type 1.5 diabetes are obese or overweight.
Misdiagnosis as having type 2 diabetes is common. Around 15-20% of people diagnosed with type 2 diabetes may actually have Type 1.5 diabetes.
Thank you so much for this reply. I asked whether the researchers included this type in their project or not because they are going to the epidemiological study
Type 1.5 has also known as Latent Autoimmune Diabetes in Adults (LADA) refers to GAD65 antibodies positive diabetes that destruct the insulin producing β-cells, with onset after 35 years of age and no insulin treatment within the first 6 months after diagnosis. LADA should be characterized as a unique metabolic profile distinct from type 1 and type 2 diabetes and shows overlap with both of these types. The patients are often present with features of the metabolic syndrome, so initially are diagnosed as type 2 diabetes. Approximately 20% with type 2 diabetes actually have LADA.
You should not include these patients in the project.
I don't think that type 1.5 is LADA diabetes....what's Nemanja just discred here as patients having Metabolic Syndrome and type 2 features is the so called Ketosis Prone type 2 Diabetes ( KPD ) and it was suggested to be called type 1.5 or even type and finally you will see in the literature KPD...they don't have antibodies different from LADA...the majority of them are afro-american or hispanic even asian.
Article Ketosis-Prone Type 2 Diabetes in Patients of Sub-Saharan Afr...
It is necessary to be careful with classifications. The present American Diabetes Association classification (2016) does not include many patients with different form of diabetes having genetic predisposition to both T1D and T2D with pancreatic antibodies.
http://care.diabetesjournals.org/content/39/Supplement_1/S13.full-text.pdf
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