Evidence shows that VIA/VILI screening tests are more economical in screening of cervical cancer in developing countries. Weather VIA alone will give better results or VILI alone will give better results or both?
An IARC multicentre study in India and Africa by Sankaranarayanan et al show that VILI has a higher sensitivity but similar specificity to VIA. It appears that VILI is a more accurate visual test to use in cervical cancer screening in low-resource settings.
We have conducted a study in our institute to establish the effectiveness of Visual inspection methods in comparasion to PAP smear for screening of cervical cancer..
In our study we found the sensitivity, specificity, PPV& NPV of Pap smear was 81.36%, 93.79%, 29.63% & 99.37%, for VIA sensitivity, specificity, PPV& NPV was86.75%, 86.06%, 16.34% & 99.43% whereas that for VILI was 86.44%, 84.38%, 15.09% & 99.49%respectively. Although the specificity and positive predictive value of Pap smear was slightly higher than the visual inspection methods there was no significant difference in the sensitivities and the negative predictive value.
Several publications show that while either VIA or VILI is as (or more) sensitive but less specific than Pap smear, either VIA or VILI is more cost-effective than Pap smear. A study has shown that among women with CD4+ count