HI

We recently purchased the cup horn Q700 Model #431C2. Our goal is to create homogeneous suspensions to achieve better consistency for our internal process of virus production. This is our first-time using sonication with a cup horn, can anyone give me a general guidelines about the different parameters and how to use this model in virus-related assays. For example: What conditions (amplitude and time) will kill/inactivate a virus versus what conditions will simply depress it? I know it may vary slightly depending on the virus itself, but having a range to start with would be helpful. Noted, the sonication will take place after sucrose gradient.

Thank you!