I have a data-set for meta-analysis (in-vivo) and I'm using ratio of means as a log(Ratio of means) to gauge the effectiveness of intervention vs control (log(mean intervention/mean of control). However, SMDH is also being reported in several meta-analysis so which calculation should I base my interpretation on? And since both (ratio of means and smd) are being used, on what basis should I use Ratio of means over SMDH and vice versa?
Thank you in advance
If your dataset is in in-vivo biomedical experiments, where outcomes are on the same scale (e.g., tumor volume in mm³, enzyme levels, body weight), log(RoM) is generally preferred for biological meaning.
Use SMD if studies measure outcomes differently or you need a standardized comparison.
standardized mean difference. it allows comparison of two or more variables, but the interpretation is less intuitive.
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