Thiostrepton -HPLC assay method

More Srikanth Voruganti's questions See All

Are there any HPLC method for determination of thiostrepton-assay ?

Any HPLC assay method for thiostrepton

27 February 2024 3,787 1 View

Determination of tween 20 using CAD detector and acclaim surfactant column ( HPLC method)?

Are there any methods for determination of tween 20 using CAD detector and acclaim surfactant column ? ( HPLC method)

13 April 2023 8,771 6 View

Quantitation of nitrites and nitrates by HPLC?

are there any HPLC methods for nitrites and nitrates which gives good response? I have issues

01 March 2023 2,126 6 View

Determination of nitrites and nitrates by HPLC

I am developing HPLC method for determination of nitrites and nitrates in pharmaceutical excipients and I am not getting good responses at Ppb levels. Is there any faster HPLC method to get proper...

01 January 1970 1,300 1 View

Poor Theoretical plates on chiralPack HPLC column

Hi I am using new chiralpack column for determination of R-enantiomers on agilent instrument but i was not able to get required theoretical plates as per the method ( Limit : NLT 2000). I...

01 January 1970 2,421 12 View

Poor Theoretical plates on chiralPack HPLC column

Hi I am using new chiralpack column for determination of R-enantiomers on agilent instrument but i was not able to get required theoretical plates as per the method ( Limit : NLT 2000). I...

01 January 1970 4,206 13 View

Negative dip on CAD -HPLC

Does anyone know why I am getting negative dip in the diluent at the same rt of active?. My mobile phase is 10mM ammonium acetate and 1-propanol (90:10) and diluent is water. column is acclaim...

01 January 1970 7,431 3 View

Sterile topical forms development ?

Can anyone in pharmaceutical development help me with some questions ? 1) When developing in R&D a STERILE topical form (ointment, cream, gel) what should be the requirements for the...

21 March 2024 2,562 4 View

Are there any HPLC method for determination of thiostrepton-assay ?

Any HPLC assay method for thiostrepton

27 February 2024 3,787 1 View

Research Medics! who received email from them for new paper project??

Do anybody receive an email from resarch medics with sweet suggestion asking the willingness of join as an authors into high IF journal publication? Who are them? is it ethically right??? Are...

05 November 2023 1,933 1 View

What is the natural alternative of CMC in cosmetics?

For gels/ointment preparation is there any natural alternatives for CMC?

01 September 2023 642 2 View

Analyzing ointments/ lipids with TOC without Solid Sample Combustion Unit, how?

For my research I have to measure carbon for cleaning validation with the TOC since I want to analyze pharmaceutical ointments. Now I understand that it is difficult to analyze this and I have...

28 August 2023 7,032 0 View

Indication of articles and studies on air in tubes of ointment. Someone can help me?

I am researching the possible cause of the occurrence of air in the ointment tubes, which affects the delivery of the product. But I'm having trouble finding references. Could you point me to...

18 August 2023 2,896 0 View

How to calculate ED50?

Ive been working with a peptide and an algae extract and for in-vivo part of the project i have to treat them as an ointment on excision wounds on rat models. so i need to calculate the ED50 of...

13 August 2023 5,713 0 View

How to study drug release from an ointment/cream loaded with compound and nanoparticle?

I have loaded 2 compounds and a nanoparticle to a cream base. I need to study the drug release of the compounds and nanoparticles individually. Please suggest me a better technique/technology for...

11 September 2022 7,745 5 View

Which type of Rotational Viscometer is good for measuring creams and ointment?

which type of Rotational Viscometer is good for measuring creams and ointment?

24 February 2022 4,102 2 View

How to decide Media for Diffusion Test in Semi Solid preparation ?

During Diffusion test for Semi Solid preparation like Gel, ointments and Cream , what will be the media for this ? Like we use different buffer solution for dissolution, same as dissolution what...

16 February 2022 5,815 3 View

Srikanth Voruganti

Iam developing assay HPLC method for ointment formulation using DMF as solvent. I tried multiple experiments but I am getting low recoveries and any suggestions on how to improve recovery?. product is oily formulation

William Letter

Srikanth Voruganti: NO NEED TO POST YOUR SAME QUESTION 2-TIMES ON RG. If you are having what you perceive to be sample recovery issues, then please provide us with the full HPLC method you are using, sample prep protocol AND the sample matrix. "Low recoveries" = poor quality method. Please be specific if you want free help.

Make sure you work with a professional chromatographer (and not on your own) to achieve success.