Thiostrepton has been an interesting drug candidate for malaria indeed. Under experimental conditions it is very effective against the malarial parasite P. falciparum. It attacks apicoplast 23S rRNA and the mitochondrial elongation factor for protein synthesis. Let's expect clinical trial first. And it will not be effective for Anopheles sinensis, because this is a mosquito - for which you will need an insecticide.
A good review a can find is this:
Article Antibiotics in malaria therapy: which antibiotics except tet...
Kholhring Lalchhandama Hello, I mean that the substance of Thiostrepton can be introduced into the mosquitoes with Plasmodium, so that it can kill the malaria parasites in the mosquitoes and fundamentally solve the problem of malaria transmission. If you can, I hope you We can provide relevant experimental literature to us, thank you very much!
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