There is some research indicating possible mitochondrial dysfunction in Psychosis. Currently a client with psychosis has been given melatonin for sleep in combination with therapies done by myself - Cognitive restructuring, talking to voices and cognitive therapy. This was after ALL normal (medical and psychotherapeutic) treatments had been applied for a 2 year period with little success before I received the client. The only two differences in treatment was talking to voices and melatonin prescribed by the doctor. Naturally this is not enough to propose that melatonin may have an impact, however there was a distinct improvement in cognitive processing abilities. Has anyone done any trials or research on the use of melatonin. Studies suggest that melatonin may or may not partially or fully repair mitochondria, whilst no research has been found on the possible utilisation of Gh.
Melatonin is included in variables examined in a workshop featured on the NIMH website at https://www.nimh.nih.gov/research-priorities/rdoc/arousal-and-regulatory-systems-workshop-proceedings.shtml
Also at NIMH a study on treatments for insomnia in psychotics that looks at melatonin at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500860/
And a study looking at nutritional treatments, at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248201/
NIMH is always a good place to start with questions of this sort, and you'll likely find even more.
Thank you Hendrika, this is very useful information and much appreciated!
Some research from my area of interest (gynecologic psychosomatics): Anderson G. The role of melatonin in post-partum psychosis and depression associated with bipolar disorder. J Perinat Med. 2010 Nov;38(6):585-7. doi: 10.1515/JPM.2010.085 and from the area of general psychiatry: van Beveren NJ, Schwarz E, Noll R, Guest PC, Meijer C, de Haan L, Bahn S. Evidence for disturbed insulin and growth hormone signaling as potential risk factors in the development of schizophrenia. Transl Psychiatry. 2014 Aug
26;4:e430. doi: 10.1038/tp.2014.52. FULL TEXT)
https://www.degruyter.com/view/j/jpme.2010.38.issue-6/jpm.2010.085/jpm.2010.085.xml
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150237/pdf/tp201452a.pdf
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