Read me: Article The gut microbiota and host health: A new clinical frontier
Questions to consider: (1) Do we find evidence of certain bacteria overpopulating/underpopulating in patients diagnosed with colorectal cancer? Are they inhibiting or contributing to cancer cell proliferation and growth? How would we measure that?
- "Intestinal microbiota and colorectal cancer: a new aspect of research" https://www.ncbi.nlm.nih.gov/pubmed/30512251
Article Dismicrobism in inflammatory bowel disease and colorectal ca...
Article Factors Determining Colorectal Cancer: The Role of the Intes...
(2) "It is now recognized that the gut microbiota and chronic liver diseases are closely linked." Would we find evidence of liver dysfunction/malfunction in those diagnosed with colorectal cancer? ( Quote from paragraph entitled "Liver disease and the gut microbiota" inArticle The gut microbiota and host health: A new clinical frontier
.)(3) If the 3 ‘P's’ for gut health are probiotics, prebiotics and polyphenols, then what effect, if any, would a SIGNFICANT increase in one of these have on a colorectal cancer patient's length of survival?
It is a very interesting study with great difficulty to perform and you must include as much patients as possible in order to get clear findings
Dear Sarah Fischbuch - I am interested in your study, and as a Guest Editor at JoVE, I invite you to submit a method study. The journal is listed in PubMed, Scopus and Web of Science. See links below for the submission and contact me for more information
https://www.jove.com/methods-collections/127/advanced-methods-in-studying-colorectal-cancer
https://www.jove.com/methods-collections/editor/201/samy-azer
Hi Samy Azer thank you for sharing and reaching out! I currently am not doing a research project on this. When you suggest I submit a method study, are you suggesting I summarize current methods and their effectiveness (e.g., a lit review)?
Dear Sarah; Thank you for your response. The journal is interested in research methodology only. We use a combination of summary and video to describe the method to readers and other researchers. Please watch videos provided on the journal website and read the link as per my invitation. I am happy to send you more details. Yes, you could use the method you had, but you need to present it from this new perspective and in innovative approach. Look forward to hearing from you. Let men know.
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