The antimalarials, hydroxychloroquine, and chloroquine that are the backbone of the treatment of rheumatologic conditions like Rheumatoid arthritis and SLE were hailed to be the "savior" of COVID19. However, that belief looks to be questionable now with the newer studies suggesting no benefit from these drugs.
Dear Dr. have a nice Sunday.
In my RG open question about the dramatic situation of Lombardia (N.Italy)
I propose the test of the natural compounds from Artemisia, according to previous extensive bibliographical reviews about toxic effect in potential biocontrol.
I hope this is useful.
RG open question and Artemisia review references: https://www.researchgate.net/post/The_novel_Coronavirus_in_N_Italy_Lombardia_COVID19_2019nCoV_SARSCoV2_shows_a_fatality_rate_compatible_with_SARS-MERS_Why#view=5eabf2ae32592944281a872b
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https://www.researchgate.net/figure/ResGa-FxFac-post_fig102_339781431
|n.2|....The following 12 virus species have been recognized, both DNA-virus and RNAvirus, both phyto-virus and zoo-virus: BVDV bovine viral diarrhea virus; COPV, canine papilloma virus; DEN/2, dengue virus 1; FIV, feline immunodeficiency virus; HBV, human hepatitis B virus; HCMV, human cito-megalo virus; HFLUV, human influentia virus; HIV, human immunodeficiency virus; HSV/1, human herpes virus 1; HSV/2, human herpes virus 2; JUNV, junin virus; TMV, tobacco mosaic virus. ....
.. ... FROM Artemisia: absinthium, afra, annua, anomala, arborescens, capillaris, caruifolia, douglassiana, herbaalba,verlotorum, vulgaris.....
.. ... Natural compounds: aesculetina, arcapillina, artemisinina, artesunate, beta-arteannuina, beta-sitosterolo, deidro-artemisinina, deossi-artemisinina, isorhamnetina, N-N-N-3p-coumaroil-spermidina, stigmasterolo.
No good news about Chloroquine/Hydroxychloroquine benefit in COVID-19 patients
After initial enthusiasm driven by President Trump labeling these as game changer for COVID-19 pandemic, there are no encouraging news even from the WHO-supervised SOLIDARITY trial.
No Hydroxychloroquine Benefit in Small, Randomized COVID-19 Trial
https://www.medscape.com/viewarticle/928798
These findings have a little bit confused me and a think these differences between studies depend on the methodologies used which differ between them
@Cheick; Methodological variation could lead to different results.
See my answer to this question:
https://www.researchgate.net/post/Does_Chloroquine_and_hydroxychloroquine_work_as_potential_therapies_against_COVID-19_or_any_other_therapies
Does not make too much difference