2 studies from first lab, 3 from the second lab and 5 from the third lab.
Christopher A Smith
Of course, there must be some level of bias, the key is to determine how much. The more rigorous the study the less bias. Please see the link to Cochrane. You can only systematically review what is there in the literature. At least you have information from three separate labs. Good luck. Hope this helps.
http://methods.cochrane.org/bias/assessing-risk-bias-included-studies
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