Researching background on glioblastoma, I know that it has among the poorest survival rates of any malignancy. However, I have found few data or studies comparing survival rates from glioblastoma with other deadly cancers. Please let me know if you are aware of any.
Thanks,
David Neil
You can get an approximate idea with poblational research such as the Cancer Statistics 2016: http://onlinelibrary.wiley.com/doi/10.3322/caac.21332/full
Glioblastoma is poor cancer but not as poor as metastatic adenocarcinoma of the pancreas, or not?!
Recently, It has been well recognized that brain gliomas, even of same grade, don't share same outcome. There are many factors that could affect the outcome.
I suggest you would read this paper; There are some patient categories that have longer survival than expected; an average 2 years or more for GBM, and 4 years or more for AA, while some have very poor OS of less than 3 months.
Article Risk stratification of pediatric high-grade glioma: a newly ...
The median overall survival of glioblastoma is around 10-12 months in population-based studies. This is actually an improvement from 4.9 months between 1984-1994. MGMT promoter methylation is a prognostic and treatment predictive marker with better outcomes and better response to temozolomide. Pancreatic adenocarcinoma has more treatment options available including biomarker based treatments, however GBM is continuing to be a hard nut to crack.
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