STZ-induced diabetic rats. Mimicking type 2 or type 1 diabetes?

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Abdualrahman Mohammed Abdualkader

Alloxan and STZ induce a type-1 like DM since both destroy the pancreatic B-cells, though by different mechanisms. To study type-2 DM, you can use either a specific rats/mice or a special diet. Check the attached paper which is directly related to this topic.

Check this paper as well