Thank you Mr. Erkan. I am synthesizing 1,2,3-triazole using click chemistry and a microwave. My starting materials are bromobenzene and phenyl acetylene. So I am expecting a triazole with two linkers (attached).

I am very grateful for the answers I could have from you.

Dear Prof.

Thank you for your replying. I spent my whole first year trying to synthesize 1,2,3-triazole compounds using phyenylacetylene with aromatic bromo compounds (e.g. bromobenzene, bromoacetophenone, bromobenzaldehyde e.t.c) but have not obtained a suitable method, despite the fact that I was advised to use the microwave for quicker, simpler and efficient method, (as in Microwave in Organic Med. Chemistry by Saddler, Kapper and Dallinger).

You could help me with any available procedure that would help me in synthesizing the 1,2,3-triazoles using the phenyl acetylene and the bromo compounds above.

Sir your help would greatly assist in conducting my research. Thank you.

Dear Professor Erkan Halay,

I have read your paper: Syntheses of 1,2,3-triazole-bridged pyranose sugars with purine and pyrimidine nucleobases and evaluation of their anticancer potential. In the paper, you have described a detailed synthesis for click reactions, so interesting of course. I have carried out similar procedure which you described in the paper. However, I used benzyl azide and phenylacetylene as my reagents. After the completion of reaction, my product does not readily dissolve in CH2Cl2:MeOH as in the paper. Your advice would greatly help.