Dear colleagues,I am working on optimizing the extraction process of essential oils and I need guidance on:

  • Which software would you recommend for creating and analyzing a Design of Experiments (DoE), specifically for:
    • Hydrodistillation time
    • Plant material/water ratio
    • Temperature
    • Drying time
    • Particle size
  • Are there any free online tools or open-source alternatives to Minitab for this purpose?
  • What would be the most suitable experimental design considering:
    • Response surface methodology (RSM)
    • Central composite design (CCD)
    • Number of variables
    • Cost and time optimization

    Any suggestions, recommendations, or shared experiences would be greatly appreciated.Thank you in advance for your help.Best regards,

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