Biserka Runje there are linear, interaction and quadratic effects. Sometimes cubic effects affect the model. The strength of the effects is based on the sum of squares from ANOVA. See the clear equations in https://doi.org/10.1007/s13399-021-01971-3
Try to experiment with Cubic effects of second order model of RSM.
You have to retry inputting the range values of your independent variables based on your pre-experimental data
No DO NOT mess around with p-values. if you chose an appropriate level it is still appropriate. You are asking the wrong questions. My fav resources on DOE and RSM are given in this link: https://www.amazon.com/Analysis-Experiments-Enhanced-Abridged-Companion/dp/1119593409/ref=sr_1_1?keywords=Douglas+C+Mo and
Please refer to these. Now your results. It appears to me that you have chosen the values for your IVs incorrectly. It looks like the temp spread is too wide. Perhaps a smaller spread but higher temps might be better. concentrate on setting the IV levels and repeating the experiment. Your figure is no help at all Good luck, David Booth PS this link may also be helpful: https://www.google.com/search?q=Box+Behnken+designs&rlz=1C1CHBF_enUS874US874&oq=Box+Behnken+designs&aqs=chrome..69i57.16692j0j4&sourceid=chrome&ie=UTF-8