Role of hydrogels and nanogels in biotechnology?

Hi,

Targeting therapeutic agents and nanotheranostics are nanobiotechnology-based approaches in disease diagnosis and treatment.

An attractive attribute of the nanocarrier systems in the are of diagnosis and nanotherapy is the ability to target and release bioactive compounds in different parts of the Human body. A recent development came from the work of Asnani and co-workers who formulated a plant-derived hydrogel beads system for targeting the encapsulated compounds to colon with the aim of colon-cancer treatment:

Asnani, G.P., Bahekar, J., Kokare, C.R. (2018) Development of novel pH–

responsive dual crosslinked hydrogel beads based on Portulaca oleracea polysaccharide35 alginate-borax for colon specific delivery of 5-fluorouracil. Journal of Drug Delivery Science and Technology, 48, 200-208.

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Asnani, G.P., Kokare, C.R. (2018) In vitro and in vivo evaluation of colon cancer

targeted epichlorohydrin crosslinked Portulaca-alginate beads. Biomolecular Concepts, 9(1), 190-199.

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Abdul Azeez

1. Chapter Nanobiotechnology

2. https://www.sciencedirect.com/science/article/pii/B9780128035818100773

You can refer the above two articles for summarized application of nanobiotechnology in hydrogels.

All the Best

Shumaila Shaukat

M. R. Mozafari what about importance of nano-gels with respect to nanotechnology,would you please suggest me

some material relevant

application of nanogels with respect to biotechnology? Abdul Azeez please if you can help

M. R. Mozafari

Dear Shumaila Shaukat

Have a look at following literature with respect of applications of nanogels:

Nanogel Applications in Biomedicine - News-Medical.Net

https://www.news-medical.net/life-sciences/Nanogel-Applications-in-Biomedicine.aspx

Rating: 4 - ‎1 voteJan 4, 2019 - The primary application of nanogels in medicine is as a payload carrier or as a delivery vehicle for drugs, diagnostic agents, or other small ...

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Nanogel - an overview | ScienceDirect Topics

https://www.sciencedirect.com/topics/pharmacology-toxicology-and...science/nanogelNanogels found a versatile application in cancer treatment. Multistimuli responsive nanogels are very effective in targeted therapy of cancer as compared to ...

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Nanogels: an overview of properties, biomedical applications and ...

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862943/

by KS Soni - ‎2016 - ‎Cited by 94 - ‎Related articlesDespite such diversity in their applications, nanogels are not yet a part of clinical use. Many comprehensive and more specialized review articles on synthesis ...

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and a useful website:

https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/nanogel

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