Not hidden from all that victims of COVID 19 does not follow regular manner, some says old ages are more vulnerable, some says smoker or patients with respiratory symptoms or asthmatic disease allergy disease were victims of severe symptoms, however, on the other hand many athletic young patients with good health were subjected to death, where is the role of the immunity here??,
So, if we run research that depends on the analysis of HLA marker among death persons especially those who were young, Do you think we can get some match and similarity, that could predict the response or prevent future deterioration?. like the marker of breast cancer or other.
It is found that HLA-B*46:01 had the fewest predicted binding peptides for SARS-CoV-2, suggesting individuals with this allele may be particularly vulnerable to COVID-19, as they were previously shown to be for SARS (1). Conversely, it is found that HLA-B*15:03 showed the greatest capacity to present highly conserved SARS-CoV-2 peptides that are shared among common human coronaviruses, suggesting it could enable cross-protective T-cell based immunity. Finally, it is reported that global distributions of HLA types with potential epidemiological ramifications in the setting of the current pandemic.
https://www.medrxiv.org/content/10.1101/2020.03.22.20040600v2
See the link please
Dear @Sura Aldewachi, thank you for your valuable information and interesting materials provided.
