Recent determination of enrichment of 64Zn in hiv infected cells and the Zn fingers in hiv virus there in caused me to reason possible new treatment and potential hiv Cures via exploiting this enrichment of 64Zn in hiv relative to heavier stable isotopes of 66Zn, 67Zn, 68Zn and 70Zn. I think the neutrino and antineutrino activities are greater for these heavier stable Zn isotopes and these heavier Zn isotopes and softer than the lighter 64Zn stable isotope. I have previously proposed stimulating the 64Zn in hiv for treating hiv and possibly enriching heavier 66Zn, 67Zn, 68Zn and/or 70Zn in hiv for weakening and inactivating hiv for a cure. Here I point out other possibilities. As the selectivity of hiv for 64Zn may arise from the hardness of 64Zn relative to the heavier stable isotopes 66Zn, 67Zn, 68Zn and/or 70Zn or the 64Zn may be less neutrino and antineutrino stimulated, I here note other possible treatment using harder and/or softer cations. I propose here using isotopes of calcium to replace 64Zn in hiv and I note calcium is special as it has a series of stable isotopes that span the magic numbers 20 thru 28 for neutrinos and antineutrino stimulations of the mid-stability isotope 46Ca. The isotopes of calcium 40Ca (96.9%) with 20 neutrons , 42Ca (0.647%) with 22 neutrons, 44Ca (2.086 %) with 24 neutrons, 46Ca (0.004%) with 26 neutrons, and 48Ca (0.187%) with 28 neutrons. The calcium (Ca) is unique among elements as its isotopes space a number of neutrons for stable magic numbers as 40Ca has stable filled neutron shell of 20 neutrons and 48Ca has stable neutron shell of 28 neutrons. BY Reginald B. Little (RBL) theory and nuclear Little Effect, the intervening stable isotopes of 42Ca, 44Ca and 46Ca span a range of instabilities for neutrino and antineutrino stimulations with 44Ca being half field neutron shell with 4 neutrons and 46Ca by RBL's theory having slight excess of half filled neutrons for greatest instability of 46Ca to fractional reversibly fissing and fusing of 46Ca for novel dynamics of 46Ca by Little Effect. But 46Ca is only 0.004% in relative abundance. If 46Ca can be enriched and administered to hiv then it may accumulate and replace some 64Zn inherently enriched in hiv cells. hiv hosts are known to be depleted in calcium (hypocalcaemia)! Giving 46Ca to hiv host would thereby intrinsically cause the patients hiv infected cells to take the 46Ca from uninfected cells. The 46Ca can thereby be targeted by Little Effect to kill hiv cells and mutate hiv virus in resevoirs. But it could be that hiv with 64Zn does not prefer the hard Ca2+ ion which have chemical similarities to Zn2+ cations. By this theory proposed here, RBL notes he can explain zinc sparks involving calcium during inception of life when sperm meets egg for another manifestion of Little Effect during life formation!!!

RBL here gives a second path of attack using softer cations of cadmium. I think cadmium would have harsher side effects than calcium (Ca) isotopes as calcium is an essential mineral. But the side effects of cadmium (Cd) can be moderated for momentary time to kill hiv. RBL here notes that if the 64Zn in hiv prefers being replaced by softer cations then the patient could be injected with radioactive 107Cd and/or 109Cd . In the Ca case I used chemical similarity of hard Ca2+ to Zn2+ to replace 64Zn in hiv. But if the softer cations are preferred then RBL here propose using softer 107Cd and/or 109Cd. As Zn and Cd are in same chemical family the 107Cd and 109Cd may replace 64Zn in hiv infected cells. RBL here involves beautiful radio chemistry to attack hiv reservoirs in host as the 107Cd and 109Cd are radioactive by inverse beta process by electron capture with half lives of 6.52hrs and 462 days, respectively, to form stable 107Ag and 109Ag. Such loading of 107Ag and 109Ag (silver) in hiv virus and hiv infected cells will kill hiv and the hiv infected cells. THis is beautiful as Ag (silver) is know to have intrinsic anti-virus properties! The silver selectively formed in the hiv virus can also be stimulated by external fields to control and inactivate the hiv virus in the host to kill the virus infected cells and inactivate the hiv virus! (April 3, 2025) - Reginald B. Little