There is potential for low doses of low LET radiation to treat viral pneumonia as a possible therapy for Covid19 patients.

LDRT treatment of 30 to 100cGy to the lungs of a patient with covid19 pneumonia could reduce the inflammation and relieve the life threatening symptoms

https://www.thegreenjournal.com/article/S0167-8140(20)30185-7/fulltext

To take to account:

A comprehensive review of literature exhibited that all the publication about LDTR for pneumonia treatment are too old and haven't been established with satisfactory scientific reliability

You may be interested in the following four papers that have thus far been published in the journals:

Article Low dose radiation therapy for COVID-19 pneumonia: is there ...

https://www.ncbi.nlm.nih.gov/pubmed/32337192

https://www.ncbi.nlm.nih.gov/pubmed/32342871

https://www.ncbi.nlm.nih.gov/pubmed/32342874

You may also be interested in ongoing discussions at

https://www.researchgate.net/post/Is_it_possible_to_use_radiotherapy_to_kill_intrapulmonary_COVID_19_to_stop_its_destroying_effect_on_lungs

Good question

No, not in this way totally, because radiation are fatal to organs like liver, lungs or any others. But one can achieve the enhancement of the hygienic quality of the consumable things may be food, medical equipment, surfaces or any other item used by people with help of process of irradiation by killing viruses like COVID-19 etc. For this purpose one can use the radiation from gamma source, electron beam and x-rays. for the 100 % eradication of this virus radiation dose can be optimized by doing some experiments.

Radiation could be used for sterilization against COVID-19, but not for therapy.

However, radiation could be used also for irradiation of COVID-19 virus and possible create a simple vaccine against COVID-19. Need check it. Who want make this project together?

Radiation can kill viruses in vitro. https://aem.asm.org/content/aem/22/1/61.full.pdf

And genetic material from killed viruses can be used for elaboration simple and cheap vaccine against COVID-19

The preliminary results of the 1st clinical trial are published. I hope in future clinical trials doses less than 1.5 Gy (the dose used by researchers at Emory University Hospital) is used. If Mohammad Khan et al. had used doses < 0.5 Gy instead of the 1.5 Gy, their 5th patient would have recovered more quickly. We were the first scientists who introduced the concept of low dose radiation therapy for COVID-19 related pneumonia. We still believe that the best therapeutic radiation dose is between 100-500 mGy, not more.

http://jbpe.sums.ac.ir/article_46588_0310a04220fde09e17224d7d0ebf59a3.pdf

Moreover, the public should be warned about the hidden dangers of antiviral drugs such as Remdesivir. Now, we know that when the treatment is not effective and viral genome replicates, selective pressure leads the virus to rapid adaptation toward resistance “An increasing number of viral infections that impair host health are treated using antiviral drugs, .... If the treatment is robust and viral fitness is impaired sufficiently, no viral genomes will be successfully replicated, but if treatment is not as effective and some genomes replicate, selective pressure may result in rapid adaptation toward resistance”.

Article COVID-19 Tragic Pandemic: Concerns over Unintentional “Accel...

The following PCP article may be of interest to some of you.

POINT COUNTERPOINT Free Access https://lnkd.in/df-5bqM Low dose radiation as a treatment for COVID‐19 pneumonia: a threat or real opportunity? SMJ Mortazavi, Amirhosein Kefayat, Jing Cai First published: 03 July 2020 https://lnkd.in/dBybYMN

Virtual workshop on LDRT for COVID-19 will be held at 9:30–15:00 EDT on 23 July. Registration needs to be completed by 15 July. Please see below for more details.

https://ncrponline.org/wp-content/themes/ncrp/PDFs/2020/LDRT_COVID_Announcement7-9-20.pdf

The STAT news article is available at

https://www.statnews.com/2020/07/16/an-old-idea-ignites-new-debate-with-clinical-trials-testing-radiation-for-pneumonia-in-covid-19-experts-remain-divided-on-its-merits/

The final PCP article is published now.

Dear SMJ Mortazavi

Thanks for sharing such a nice work.

Congratulation

COVID-19 has been reported to effect the human's lungs and liver . I radiation therapy is used then the tissues of the organs will be damaged. Hence , use of radiation therapy has not been recommended.

Dear Madhukar Baburao Deshmukh

But Radiation dose is calculated keeping in mind the sensitivity of the tissues or organs.

The following two new papers came out this week in the Red Journal

https://www.redjournal.org/action/showPdf?pii=S0360-3016%2820%2931444-9

https://www.redjournal.org/action/showPdf?pii=S0360-3016%2820%2931445-0

A statement has just been released from UK.

https://www.rcr.ac.uk/sites/default/files/statement-on-ldrt-for-covid-19-pneumonia_jul2020.pdf

Article Unethical not to Investigate Radiotherapy for COVID-19

On August 23, 2020, the U.S. Food and Drug Administration issued an emergency use authorization (EUA) for investigational convalescent plasma for the treatment of COVID-19 in hospitalized patients. FDA report states that "“The FDA’s emergency authorization for convalescent plasma is a milestone achievement in President Trump’s efforts to save lives from COVID-19,” said Secretary Azar".

However, there are distinguished scientists who believe that although convalescent plasma (CP) is promising and saves lives but not to the extent that was described by the head of FDA on 8-23-2020. This is exactly the reason that our international team suggested using a hybrid method that can maximize benefits for COVID-19 patients, i.e. low dose radiation therapy (LDRT) and convalescent plasma. LDR, not only has anti-inflammatory effects but also optimizes the activity of the immune system. We believe that a hybrid treatment including both CP and LDRT can trigger synergistic responses that will help healthcare providers in mitigating today's COVID-19 pandemic. Source: Low Dose Radiation Therapy and Convalescent Plasma: How a Hybrid Method May Maximize Benefits for COVID-19 Patients. J Biomed Phys Eng https://www.ncbi.nlm.nih.gov/research/coronavirus/publication/32802787 PMID: 32802787, PMC7416097

Dear SMJ Mortazavi

Thank you very much for such a wonderfull information.

You may be interested in the new paper on the reanalysis of early radiobiological data about pneumonia after bacterial or viral infection preceded or followed by radiation exposure.

Article Pneumonia After Bacterial or Viral Infection Preceded or Fol...

A meeting report of the virtual NCRP/NCI/NIAID workshop on LDRT for COVID-19 held on 23 July 2020 has just come out

https://meridian.allenpress.com/radiation-research/article-abstract/doi/10.1667/RADE-20-00211.1/445871/Low-Dose-Radiation-Therapy-LDRT-for-COVID-19

How Did COVID-19 Scandal Affect the Global Attention to Low Dose Radiation Therapy?

Article Anti-inflammatory effects of low-dose radiotherapy

Could be helpful for understanding mechanisms of therapeutic action of radiation against severe COVID-19 pneumonia. However, for me, personally, hormonal therapy with dexamethasone seems more logical, effective and safe.

The final version of the meeting report of the virtual NCRP/NCI/NIAID workshop on LDRT for COVID-19 held on 23 July 2020 has just come out and is now downloadable

https://ncrponline.org/wp-content/themes/ncrp/PDFs/2020/RADE-20.pdf

Hello

Follow our paper

Article Nano Antiviral Photodynamic Therapy: a Probable Biophysicoch...

Yes, we can through Ak-Tom technology. See my last manuscript pre-print just published.

Hello and thank you,

Thanks for the article and its index.

Hi,

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