I'm working on two proteins (A and B) that are highly expressed in a disease. When the level of A increases in the blood, the level of B also increases (n= 100). Is it possible to show a correlation between the increase of these two proteins using a heatmap, Rstudio (heatmap for 100 patients)
#Biostatistics, Heatmap, R studio, correlation
Yes, you should be able to. I would start with this tutorial if I was attempting it myself: https://rpubs.com/lumumba99/1026665
To visualize the correlation between proteins A and B in 100 patients using a heatmap in RStudio, load libraries like 'ggplot2' and'reshape2', create a sample dataset with patient IDs, and calculate the correlation matrix using the cor function. Melt the matrix into a heatmap format using the'melt' function from the'reshape2' package. Use 'ggplot2' to create a heatmap, mapping color intensity to correlation values. The resulting heatmap visually represents the correlation between proteins A and B, with color variations indicating strength and direction.
Yes, you can. Use this function, cor(your_data) to create the correlation matrix. Make sure your data is numeric. Then, use function ggplot() for visualization. You need these two packages, ggplot2 and dplyr to make thesefunctions work.
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