Hi all,
What reference strains that I can use as a positive control for detecting fluoroquinolone-resistance genes?
Thank you in advance.
You can use ESBL-producing E. coli and Klebsiella pneumoniae (already positive for fluoroquinolone resistant gene) strains for detecting fluoroquinolone resistance genes.
You can use ESBL-producing E. coli and Klebsiella pneumoniae (already positive for fluoroquinolone resistant gene) strains for detecting fluoroquinolone resistance genes.
Abhishek Dharm Singh
Thank you so much for your help!
That’s a good idea. I only couldn’t find a source for fluoroquinolone-resistance genes that they harbor.
You can find many ATCC cultures which harbor this resistant gene. I have found this one (Klebsiella pneumoniae (Schroeter) Trevisan (ATCC® BAA-2788™)) which have shown to be resistant to fluoroquinolone (Levofloxacin, Moxifloxacin etc.). The strain have been positive for many resistant genes.
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