A model organism is one which is studied to further our understanding of biological processes. Typical characteristics of model organisms include developing to maturity rapidly, the ability to be easily manipulated, having a short life span, producing a large number of offspring and to having a sequenced genome, in addition to being well understood. Model organisms, if possible, need to have cheap sources and be easy to store in a laboratory as well as being non-pathogenic.
e.g.
- WormBook: The Online Review of C. elegans Biology [Internet].
Pasadena (CA): WormBook; 2005-2018.
- Helicobacter pylori: Physiology and Genetics.
Mobley HLT, Mendz GL, Hazell SL, editors.
Washington (DC): ASM Press; 2001.
- C. elegans II. 2nd edition.
Riddle DL, Blumenthal T, Meyer BJ, et al., editors.
Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 1997.
- The Cell: A Molecular Approach. 2nd edition.
Cooper GM.
Sunderland (MA): Sinauer Associates; 2000.
Hi Mohammed ,
You may find these articles relevant too.
1. Leonelli, S., & Ankeny, R. A. (2013). What makes a model organism?. Endeavour, 37(4), 209-212.
2. Davis, R. H. (2004). The age of model organisms. Nature Reviews Genetics, 5(1), 69-76.
3. Rédei, G. P. (1975). Arabidopsis as a genetic tool. Annual review of genetics, 9(1), 111-127.
4. Spitsbergen, J. M., & Kent, M. L. (2003). The state of the art of the zebrafish model for toxicology and toxicologic pathology research—advantages and current limitations. Toxicologic pathology, 31(1_suppl), 62-87.
5. Fields, S., & Johnston, M. (2005). Whither model organism research?. Science, 307(5717), 1885-1886.
Thanks.
Hi Mohammed,
Drosophila melanogaster remains one of the most intensively studied model organism.
Some books about Model organisms :
- The Biological Resources of Model Organisms : Collection, Characterization and Applications - by Robert L. Jarret and Kevin McCluskey
- The Cricket as a Model Organism: Development, Regeneration, and Behavior - by Hadley Wilson Horch, Taro Mito, et al.
- X is for Xenopus: A Model Organism ABC Book - by Marisa Claire Yadon | Jun 19, 2019
- Mouse as a Model Organism: From Animals to Cells - by Cord Brakebusch and Taina Pihlajaniemi
Joseph Schapira
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