can anyone suggest that which compartment model (One compartment model, Two compartment Model etc.) is usually followed by Tizanidine HCl after releasing from sustained release oral dosage form, and meloxicam released from immediate release dosage form of Meloxicam after the single oral dose?
Hi , what exactly want to say ..? I'm not sure if iI understand your question. Can you please rephrase your question .?
I just want to know that when we administered tizanidine hcl and meloxicam through oral route, which compartment model they will follow??
It is possible to get the idea about Pharmacokinetic parameters of Meloxicam by oral route assuming one compartment.
Hi Muhammad, According to Mathias et al., Pharmacodynamics and pharmacokinetics of the oral antispastic agent tizanidine in patients with spinal cord injury (1989) Journal of Rehabilitation Research and Development, 26(4), pp.9-16 it seems to be a 1-compartment model for the immediate release oral administration.
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