Out of Balb/c and Swiss albino which model is best to study effeciency and toxicity of antimalarial compounds against Plasmodium falciparum infection?

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What degree of missing data in a particular case/participant results in Expectation-Maximisation no longer working?

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Do anyone here can help us in the field of molecular docking?

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Why does intensity drops as concentration increases?

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RNA-seq DEGs downstream analysis and reporting in literature?

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Hiba Riyadh Al-abodi

https://www.sciencedirect.com/science/article/abs/pii/0006295289906448

Moses Mwajar Ngeiywa

Swiss albino mice model has been used extensively in effects of various chemical compounds as in vivo system. We have used this model to evaluate efficacies of several plant compound extracts against Leishmania parasites. If the mice can get infected with Plasmdium falsiparum, I will recommend this model.

Swaroop Kumar Pandey

Priyanka, Since development of anti-malarial is not a personalized medicine approach and its population based, you should use outbred Swiss albino rather than using inbred BALB/c.

https://www.researchgate.net/deref/https%3A%2F%2Fwww.sciencedirect.com%2Fscience%2Farticle%2Fabs%2Fpii%2F0006295289906448