A neighborhood magazine featured a story on MTHFR mutants and the regulation of folate. According to the article, Fibromyalgia is on of the syndromes associated with MTHFR gene mutations. Any validity to this?
Neil R Mcgregor
There is one paper that links MTHFR with fibromyalgia but I am unaware of any that implicitly link the polymorphisms of this gene with ME/CFS. The gene is linked to temporomandibular joint disorders in 1 paper as well.
Fibromyalgia, mood disorders, and intense creative energy: A1AT polymorphisms are not always silent
Donald E. Schmechela, b, Corresponding author contact information, E-mail the corresponding author,
Christopher L. Edwardsc, d
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