OpenFOAM is a popular, open source, versatile CFD simulation software and definitely capable of simulating microfluidic droplet generation (see e.g. Article Investigation of Different Droplet Formation Regimes in a T-...
andThesis Study of Microfluidic Mixing and Droplet Generation for 3D P...
).But setting up a working, validated initial scenario (PDMS boundary conditions, fluorinated oil viscosities, surface tension with PicoSurf, friction, meshing, etc.) is difficult and work intensive. On the other hand, if there was an open source dataset/workflow to get started, it would be relatively easy to modify and extend it. Can you suggest an available starting point?