Hello everybody. Do anyone here have a complete method for synthesis iodobutane using an SN2 Mechanism? The reagents are bromobutane, NaI and acetone as the aprotic solvent. I need the complete method, my professor wants the radio of reagentes and everything. I already have an ideia of what I have to do but would deeply aprecciate with someone could help me in this.
Dear Ana Julia Aparecida Ramos ,
I think you want to perform a Finkelstein reaction. You may find easily what you need on specialized website. For example Organic Chemistry Portal:
https://www.organic-chemistry.org/namedreactions/finkelstein-reaction.shtm
I hope my answer could help you.
Corentin Lefebvre I used Scifinder and found one :) But thank you, always good to learn! Have a great week.
For the synthesis of iodobutane, take n-butyl tosylate prepared by the reaction of n-butanol with p-toluenyl sulphonyl chloride ad treat with KI or NaI to get desired product.
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