if there are membrane-bound and others soluble forms of an interleukin
as well as we find pro interleukin and mature form....
we know there are decoy receptors and ligands for cytokines
we know there are transiently elevated
we measure as researcher sometimes the interleukin in tissue as in immunohistochemistry
other estimated levels in biofluid like serum or saliva ......
my question starts here? are there any compensatory mechanism or hemostasis for cytokines?
(calcium and parathyroid hormones)
or difference between tissue expression and serum level ? or they (decrease/increased) in a parallel manner?
with best regard