I am planning to form conjugate between amino acid and compounds with hydroxyl groups. I would like to know more about the basic protocol that could be performed to form stable complexes.
The easiest way to activate OH group is to use carbonyldiimidazole or N,N'-disuccinimidyl carbonate, then the active group can be reacted with an amine-containing molecule. You can also use epoxides or oxiranes but they require high pH.