LRRK2's place in the MAPK pathway?

22 October 2018 0 9K Report

Hi all,

I am trying to understand how is LRRK2 linked to the kinases in the MAPK pathway and how it fits into the immune response. Some papers are suggesting IKK having an effect on LRRK2 and others suggesting LRRK2 having an effect on MAPK and MKK.

Can anyone please comment on how they are all interlinked and the sequence in which these activations occur?

Thank you very much in advcance.

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