I am looking for works and publications dealing with Huge Grain Modelling (HGM), with a specific interest in modelling of large protein assemblies.
By HGM, I mean a really coarse representation. Typically in the context of protein assemblies, subunits will be represented by a small number of large beads. This approaches are typically used when the structure of the proteins is not known.
Two good examples of such approaches are :
- The modelling of the Nuclear Pore Complex proposed by Alber et. al.
http://www.ncbi.nlm.nih.gov/pubmed/18046405
http://www.ncbi.nlm.nih.gov/pubmed/18046406
- The modelling of a gene or a chromosome based on spatial restrains by Bau et. al.
http://www.ncbi.nlm.nih.gov/pubmed/21131981
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