Lanthanide (CyTOF) labeled Ab coupled with MALDI

23 May 2017 1 3K Report

Is that possible to use lanthanide-labeled antibodies (for CyTof) with MALDI instrument instead of LA-ICP-MS to get MS image? Did someone tried?

Jianing Wang

I never tried. It is a good idea, despite that the sensitivity may be low. In addition, the spatial resolution should be lower than cyTOF.

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