Is there NTP/dNTP/rNTP analogue that can stall DNA polymerization at a specific base??

05 October 2020 1 6K Report

For example, if the template sequence is CGTTCA and I use a certain dATP analogue, can my inserted sequence be GCA (as no further A can be added after dATP analogue insertion)??

Omkar Singh Kushwaha

It is really challenging task to stall it in a required way.

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