One of my undergrads created a phylogeny based on few human hCov19 and few from other hosts including bat, panguline, and dog. He found two viral genomes one from an Australian and one from a Singaporean clustered with the one isolated from canine. This seems interesting! Any study to support this finding?
The transmission of SARS between dogs and humans has not been established with SARS, but the presence of the virus has been proven in the tears of humans. This did not happen in Corona Virus.
The intermediate host between bat and human have yet not been concluded. It could be panguline due to similarity of receptor . However till final conclusion dog can also studied as one of differential diagnosis.
Mali S, Pratap A, Thorat B. The Rise of New Coronavirus Infection-(COVID-19): A Recent Update. EJMO. 2020; 4(1): 35-41
Dogs are less susceptible to the SARS-CoV-2 infection. Hence, they do not play a role in the epidemiology of COVID-19. However, dogs can become infected by the virus, but they do not get sick. Dogs are much more resistant to the virus and are unable to transmit the virus to other animals or humans.
to the best of my current knowledge, there is antidotal reports of free-ranging canines exhibting respiratory distress principally form an island microenvironment in mainland China. I have not seen any documented or experimental based reports of canine - COVID 19 involvement.
A reasonable quick experiment would test canine bronchial cells for the spike receptor protein with the assumption that the virus uses the same cell membrane receptor in humans, felines and canines. SARS-CoV can be recovered from ferrets in controlled experiments. The secondary question if canines are permissible to COVID19, is the virus transmissible from canine to canine. The canine may be infectable, but a dead-end host.
A better question may be "wat about the other recently isolated novel cornaviruses? It may be that SARS-CoV was a "wake-up call", ignored but by a few. But as long as humankind "invades & displaces" indigenous flora and fauna habitats, humankind is susceptable. A good reference is the book "Spillover".
Zoonotic diseases are one price that humans paid for changing from a hunter gatherer society. Of course, that can work both ways and animals pay the price too, directly and indirectly.
The fundamental problem is surely not our relationship with animals as a source of food, companionship and co-operation, but the superstition that leads to pangolins and bats, for instance, being sold in the first place and handled poorly?
The closer that countries come to having a comprehensive, modern, affordable health system for all, the less people will rely on hokum, be that of the "eye of newt" variety or the latest snake oil promotion such as the recent fad for cannabinoids.
In cooperation with a move towards decent animal welfare, this has the potential to lower the risk to humans from zoonotic infections.
Xia's paper (https://academic.oup.com/mbe/advance-article/doi/10.1093/molbev/msaa094/5819559) suggesting that dogs are a vector seems to have been dismissed as poor research (https://www.dogsnet.org/pariah/) and, although it certainly seems that dogs can be a fomite for SARS-COV-2, transmission so far seems to be more of a danger from dogs contracting it from humans than vice versa. It may be a different matter for cats though.
Dear Sir,
I found an article published on March 31st, 2020 as a pre-print in BioRxiv by Chinese scientists from State Key Laboratory of Veterinary Biotechnology. They said that SARS-CoV-2 replicates poorly in dogs but efficiently in ferrets and cats. They inoculated five young dogs with SARS-CoV-2 and found that two excreted viral RNA in their faeces, but none contained infectious virus. Here is the link to that article and a news report by Nature related to the topic-
https://www.biorxiv.org/content/10.1101/2020.03.30.015347v1
https://www.nature.com/articles/d41586-020-00984-8
Hope you find them useful.
Felines can certainly be infected. In the Bronx Zoo (New York, USA) eight big cats (five tigers and three lions) tested positive for SARS-CoV-2, probably infected by an asymptomatic zookeeper:
Seven more big cats test positive for coronavirus at Bronx Zoo
https://www.nationalgeographic.com/animals/2020/04/tiger-coronavirus-covid19-positive-test-bronx-zoo/
Dogs can be infected too, but they seem to be less susceptible:
Article Coronavirus can infect cats — dogs not so much
Dear Dr. have a good Sunday.
In my daily update of COVID19 dramatic phenomenon in Lombardia (N.Italy)
I reviewed (date: ►2020 Aprile 18► ) all the official documents of
Technical Report 2019nCoV or SARS-CoV/2 Coronavirus {Riboviria Nidovirales Co...
-- animals & pets with SARS-CoV/2 positive tests
-- animals & pets with as possible reservoirs of SARS-CoV/2 {Felis, Canis, Bos, Capra, Ovis, Sus, Columba, Gallus |-|-| cats, dogs, cows, goats, sheep, pigs, pigeons, chicken.. }
with an extensive document reviews at end of pdf.
I hope is useful.
Although, SARS-CoV-2 has been detected in domestic dog and zoo tiger, there is no scientific evidence of transmission to humans.
https://www.vox.com/coronavirus-covid19/2020/4/6/21209474/coronavirus-tiger-covid19-animals-bronx-zoo
A betacoronavirus beta_JX 860640.1, had been studied from dog and another one beta_MG 757188.1 studied from cat (Chinese publication)
Have a look at these useful RG links.
Article Possible human-to-dog transmission of SARS-CoV-2, Italy, 2020
Article First evidence of human‐to‐dog transmission of SARS‐CoV‐2 B....
Also see the following RG link.
Article Investigation of SARS-CoV-2 infection in dogs and cats of hu...
Dear Muhammad Maqsud Hossain
See kindly the following useful RG link: Article First evidence of human‐to‐dog transmission of SARS‐CoV‐2 B....
Kindly see also the following very good RG link: Article SARS-CoV-2 at the human-animal interface: A review
Also check please the following good link: https://www.nature.com/articles/s41586-020-2334-5
The following RG link is also very good:
Article SARS-CoV-2 Infection in Dogs and Cats: Facts and Speculations
More than two years after the declaration of a "pandemic", confusion continues to reign supreme.
Transmission of SARS-CoV-2 from humans to other mammals, including pet animals such as dogs, cats, etc., has been reported. However, with the exception of farmed mink, there is no previous evidence that these infected animals can infect humans, resulting in sustained human-to-human transmission. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)00326-9/fulltext
Check https://pubmed.ncbi.nlm.nih.gov/33979566/
https://www.cdc.gov/coronavirus/2019-ncov/daily-life-coping/animals.html
The main concern is not the dog' health but the potential risk that dog may act as an incubator of the virus and reintroduce it into people.
Speak for yourself! There are plenty of owners who would be extremely concerned for the health of the dog, myself included.