Have you checked "The Ethics of Clinical Trials Research in Severe Mood Disorders" by Nugent et al., 2017. It focuses on both major depressive disorder and bipolar disorder meaning it deals with both types of the disorder and also focuses on clinical groups as you need :)

Best Xavier,

I believe that it may be of importance to define what "therapautic milieu" comprise... One possible part of the milieu, and in my opinion a very important one, may be the staff and then attitudes they have. I suggest that you read the paper below, which is a good exemple of this.

Thank you Mr. Pontus. I read the article. I would like to know any interventional studies on therapeutic milieu for patients with depressive disorders.

Most welcome!

I will try to find articles on interventional studies on therapeutic mileu for You! Best regards, Pontus