Yes, standardized iso-volume and iso-intensity protocols for rat swimming and treadmill training exist. Treadmill protocols often involve progressive speeds, inclines, and durations, while swimming typically uses controlled water depths and weights.

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For comparing adaptive changes in swimming and treadmill training protocols in rats, Iso-volume or Iso-intensity methods can be used:

Swimming Protocols:

- Iso-intensity:

Swimming at a fixed speed or resistance (e.g., adding weight) for 20–60 minutes, 3–5 times per week.

- Iso-volume:

Fixed duration of swimming (e.g., 30 minutes) at self-selected speed.

Treadmill Running Protocols:

- Iso-intensity:

Running at a fixed speed (e.g., 50–70% VO2 max) for a set time (30–60 minutes).

- Iso-volume:

Running for a fixed duration (30–60 minutes) regardless of speed, 3–5 times per week.

In both cases, consistent intensity or volume is necessary to compare control and experimental groups.