How to determine pka of 1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) in propionitrile at -40 C?

The pka of DBU in acetonitrile is 24.34. The pKa values are affected by temperature and the solvent dielectric constant. Is there a formula to convert pka values from one solvent to another as...

02 March 2016 7,503 1 View

How to crystallize product that crash out from an aqueous solution?

I run my reaction in water and leave it for slow evaporation. The product crashed out after a week, which are not suitable for X-ray crystallography. I have tried to dilute the product and slowly...

01 February 2016 907 3 View

What solvent and electrolyte combination is suitable for a large potential window with glassy carbon electrode in non-aqueous condition?

01 February 2016 3,639 4 View

Why does the GC electrode get oxidized with 1M NaOH?

I have been trying to get a background CV with 1M NaOH. As soon as I do IR compensation, the program says "Resistance is TOO HIGH". I can see bubbles forming in the GC electrode and auxillary Pt...

07 August 2015 672 9 View

What is the best way to crystallize sodium hydroxide for electrochemical studies?

I have tried to crystallize with sodium hydroxide with ethanol. However, I can still see a peak at 1.3V vs. Ag/AgCl in my CV graph.

05 June 2015 4,474 3 View

How does an Ocean-Optics HIOXY oxygen sensor work?

I am curious how this system work?

04 May 2015 7,513 2 View

I am getting flaky solids after crystallization. What kind of solvent system should I used?

I have been trying to crystallize my metal complex with slow diffusion of diethyl ether in acetonitrile and methanol. However I am getting flaky solids, instead of crystals. Could you share any...

04 May 2015 1,497 5 View

Polymer composites suddenly solidifies?

I am making polymer composite by solvent mixing method. When I am trying to add filler solution in polymer solution it quickly get solidified. How to make them then uinform? It doesn't give time...

03 March 2021 7,540 4 View

What solvent can I used for Paal Knorr reaction between 6-amino hexanoic acid and 2.5 hexanedione?

I am try to make the Paal Knorr reaction between 2.5 hexnedione and 6-amino hexanoic acid, my problem is type of solvent to use, because 6-hexaminohexanoic acid is soluble in water but I am not...

02 March 2021 4,443 2 View

How to polymerize TEOS?

I want to polymerize TEOS on a surface. I know that NH4OH is a preferred catalyst and an alcoholic solvent should be used .But I can not find certain amounts of each material to use. Does any one...

02 March 2021 1,404 6 View

How to calculate BREQ 3 questionnaire?

how to calculate BEHAVIOURAL REGULATION IN EXERCISE QUESTIONNAIRE BREQ 3 ,which contain 24 questions and each question has 5 answers (0- Strongly disagree , 1-disagree, 2- Neither agree nor...

02 March 2021 811 3 View

I am interested in medicinal chemistry field, which books are highly recommended to learn from?

I am at the beginner level in drug design and drug discovery, and I am interested to learn more about this field. Which books are highly recommended to start from and gives me all essential...

02 March 2021 8,437 2 View

Please suggest a good text book for "Research Methodology in Life Sciences". Which book would be good for PhD Scholars?

Please provide Book Title and author name

02 March 2021 9,059 3 View

Could any one guide me, to write research proposal for grant? ?

We have one plant, the local people using this for controlling blood sugar, the toxicity and antidiabetic activity of the plant is not reported yet, please guide from whag should be the process ?...

02 March 2021 2,300 1 View

How to quantify carbon deposition on CuZnAl catalyst?

Dear All, I want to quantify carbon deposition on the surface of the CuZnAl catalyst. I have tried thermogravimetric analysis, but I've got weight gain as the active Cu- get oxidised. Does anyone...

01 March 2021 1,907 3 View

How can extract ciprofloxacin hydrochloride disolve in water er to organic solvent such as dichloromethan or any other solvent?

I need a procedure to extract the ciprofloxacin hydrochloride from aqueous solution by using dichloromethane in detail,. I thank you very much.

01 March 2021 4,306 1 View

How to separate water from glycerol solvent in a solvent recovery vacuum distillation column?

I am currently doing my third year design project. I have been assigned to design a glycerol recovery column in vinyl acetate monomer production. The process unit before the recovery column is an...

01 March 2021 9,525 4 View