What about trying to explain the virus microbiome interactions through the functional relations or even structural relations between viral miRNAs and bacterial small RNAs even through host miRNAs, that could be implemented to diabetes as well.
Microbiota inhibit infection of some viruses and promote infection of other viruses. These effects can occur through direct and/or indirect effects on the host and/or virus.
1. Human norovirus binding to select bacteria representative of the human gut microbiota Erin A. Almand1 , Matthew D. Moore2 *, Janie Outlaw2 , Lee-Ann Jaykus
2. Robinson CM, Pfeiffer JK. Viruses and the Microbiota. Annual review of virology. 2014;1:55-69. doi:10.1146/annurev-virology-031413-085550.
3. Ichinohe, T. et al. Microbiota regulates immune defense against respiratory tract influenza A virus infection. Proceedings of the National Academy of Sciences of the United States of America 108, 5354–5359, 10.1073/pnas.1019378108 (2011).