I'm looking for some OFFLINE software or R package which can do the GO enrichment analysis and the GO clustering just like DAVID.
Dose anyone know ?
Try this Bioconductor Package: "clusterProfiler". Very powerful.
Good luck
I'm using this package,but it seems not so convenient for the GO clustering, which could get a result like this .
Annotation Cluster 1 Enrichment Score: 7.621268229661738
Category Term Count % PValue
GOTERM_CC_FAT GO:0044459~plasma membrane part 288 19.72603 8.54E-18
GOTERM_CC_FAT GO:0005886~plasma membrane 420 28.76712 1.11E-13
GOTERM_CC_FAT GO:0031226~intrinsic to plasma membrane 146 10 1.97E-06
GOTERM_CC_FAT GO:0005887~integral to plasma membrane 139 9.520548 1.48E-05
GOTERM_CC_FAT GO:0031224~intrinsic to membrane 498 34.10959 0.002228
GOTERM_CC_FAT GO:0016021~integral to membrane 481 32.94521 0.003023
clusterProfiler is a powerful package for enrcichment analysis,but I don't know how to do this.
Also, how to register a david account? I can't find the link on the website
I got the David account already!!!through this link https://david.ncifcrf.gov/webservice/register.htm
http://www.pantherdb.org/
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