In our lab we got good results on inhibitory activity of some of plant extracts on fungus by in-vitro study and I would like to continue the study in-vivo using rats. We tried many methods but we couldn't standardize the method . Can anyone share their experience and help me out further?
It all depends on type of fungus, most of fungus-rats studies are done on deuteromycetes, and Pulmonary Aspergillosis
Yes you can If mice are the animal model for the fungus you are working with.
If you have good result of in vitro experiment. You can go for anti-inflammatory, anti-cancer or anti-Melanin synthesis with the rat. There are so many articles were published.
May I ask you: what kind of fungus do you study?
Thank you all for suggestions I could not reply for long due to personal reasons. Sorry for that. We used dermetophytes -Trichophyton rubrum,T-Mentageophytes, Epidermaphyton flocossum in rats . But We could not inoculate in it can you suggest mesome articals gives the methods to do it.
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