Is there any handy program / way to make irregular grids that could be used in DELFT3D?

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Nahide I. Huseynova

The Matlab program has two-dimensional interpolation and visualization functions on an irregular grid

Renan Ribeiro

I think the best program for this is the tools provided by the Delft3D suite, such as RGFGRID

https://content.oss.deltares.nl/delft3d/manuals/RGFGRID_User_Manual.pdf