To answer you this properly, it is necessary to have more details about the experimentation model you might be talking about, and of course, what your working hypothesis are.
I want to induce and recover stroke in animals rats, mice or gerbils and relate it with hypertension. So, for this i want to develop a model that first cause hypertension in animals and then stroke due to high blood pressure. Is there any experimental model that induce hypertension that leads to stroke? Also, is there any way to determine stroke due to hypertension and its recovery?