Clearance time indicates the speed of disappearance of a drug from an organ, the plasma or the body
Withdrawal time indicates the (minimum) time between (last) application of the drug and possibility to deliver once again milk, eggs etc or slaughtering the animal for human consumption.
According to the Ist order kinetic law, If the drug is following first order kinetic in its elimination , about 99.4% of the drug will be eliminated aftre passing 5 half lives.,. if the half life of the drug is is 4 hrs, it means after 20 hrs 995$ is eliminated from the biological system
There positively should be a correlation between clearance of the drug and the appearance of withdrawal sings and symptoms.
Withdrawal signs or symptoms are physiological or pharmacological phenomena.
They are not related to withdrawal (also called waiting) times, that are (legal) limits to prevent unwanted residues of drugs to occur in animal products for human consumption.
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