Hi. I have modeled a protein using threading algorithm. Total residues 424 and out of which 3.8% are in not allowed region 4% in generously allowed region. Of them, most of them are terminal residues and Proline residues.
I have tried various modeling method and servers and this structure showed maximum justice.
Any comments.
The 5% is used in research except 0.5% or less is used when a mistake in the conclusion causes risk to life and safety. There are 5 levels of risk with level 1 being 0.5%, and level 5 being 0.00005%. Levels of risk are decided in a table comparing potential severity with expected frequency of occurrence. In the same sequence the 5% can be thought as a risk level of zero.
Not everyone uses the same decision table. Decades ago in training programs I heard of large petroleum operations in which less than two fatalities qualified as risk level 1. Many times I worked in small industries where a disabling injury qualified as risk level 5.
The cost of mitigation, laws, standards, and numbers of people employed enter into construction of the decision table. Along with the decision table there is a mitigation table that to a large extent applies equivalent levels of prevention, protection, and mitigation to equivalent levels of risk. The mitigation table tends to be constructed differently for different sizes and types of operations.
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