Is there a way to use exosomes to specifically target a cargo delivery to a subcellular organelle (such as peroxisomes...) in specific cell types??

05 March 2018 0 9K Report

Anyone crossed a publication or is familiar with a research on using exosomes as drug delivery system that can specifically target a particular cell type and even more specifically target some organelles inside the cells such as peroxisomes or mitochondria or such.

Badges
Science topic

Similar topics
Phytochemistry
Extracts

More Adel Driss's questions See All

Provided that the shale conductivity termed here x increases with temperature, how could we compute it at reservoir temperature ?

one could use Waxman and Thomas (1974) work?

22 July 2024 6,637 0 View

Is there a difference between the curriculum and the style of the study?

A question about scientific methodology

13 July 2024 2,160 8 View

How Bpai (Branson dental operator posture assessment instrument is scored? How the total score is 194?

Hello Everyone, May I ask you to explain how the total score of BPAI is summed to 194? I know the scoring of modified BPAI well, but I need the original form. This is a link to the...

20 June 2024 7,284 0 View

How can biocatalysis be integrated into larger carbon conversion processes, such as biorefineries or waste valorization schemes?

biocatalysis can be integrated into larger carbon conversion processes, such as biorefineries or waste valorization schemes. The main question: HOW

18 May 2024 2,869 0 View

What are the environmental benefits of using biocatalysis for carbon conversion compared to traditional chemical methods?

The environmental benefits of using biocatalysis for carbon conversion compared to traditional chemical methods are large. What are they?

18 May 2024 3,620 0 View

Are there any recent developments in the discovery or engineering of novel biocatalysts for carbon conversion?

Developments in the discovery or engineering of novel biocatalysts for carbon conversion cannot be stopped. we need to know any recent deevelopment in this field.

18 May 2024 5,345 1 View

What types of carbon sources can be effectively converted using biocatalysis?

Types of carbon sources can be effectively converted using biocatalysis

12 May 2024 2,389 1 View

What are the strategies for optimizing biocatalysts for carbon conversion?

For carbon conversion , the use of biocatalysts must be optimized, so what are the strategies used for this purpose?

10 May 2024 7,839 1 View

How efficient are biocatalysts in converting carbon sources into valuable products compared to traditional chemical catalysts?

The biocatalysts can be more available than traditional catalysts? The quation is related to the sustainablity by conversion of carbon using biocatalysts.

04 May 2024 9,761 2 View

Is the relationship A=-Log T applicable for calculating the absorbance, in the case of thin layers?

16 April 2024 9,740 2 View

Why Do TDS and EC Increase with Larger Wastewater Volumes, While BOD and COD Decrease?

I have carried out MFC experiments on three different volumes, 50, 500 and 1000 mL of wastewater. Results after MFC treatment shows that TDS and EC are more in larger volumes of water i.e. TDS and...

09 August 2024 9,621 0 View

Could it be a cell culture contamination?

Hello everyone! I observed in my culture (htert-RPE1 cells) an orange- red particle at the bottom of the dish. It is visible to the naked eye as a very very small red dot. Could it be a...

09 August 2024 2,824 3 View

Is there any way to quantify bacterial and fungal cells in their mixed culture?

I am working in fungal fermentation of soybean meal and there is bacterial growth in them at times. I am trying to quantify fungal cell counts and bacterial cells; but I haven't been able to do at...

07 August 2024 7,535 4 View

How to normalize and take the significance of the MTT OD values with 3 replicates for the same cell-line?

Hi, I have a question about normalizing the MTT OD values for doing the statistical analysis. So, if we have 3 different plates and we call them 3 different replicates, so, first we would...

07 August 2024 8,106 4 View

Why activated CAR-Jurkat cell could not kill targets?

Previously when I co-coluture anti-CD19(FMC63) CAR-Jurkat with Raji with E:T=5:1, Jurkat can eliminate Raji in 24h. However, when I test another CAR construct, although I can dectect totally CD69...

06 August 2024 641 2 View

How to isolate lymphocytes from mouse spleen?

I have tried several times to isolate lymphocytes from mouse spleen, but all attempts have been unsuccessful. I tried most available protocols. I used different dissociation media (HBSS with Ca...

04 August 2024 9,913 7 View

How to Add Missing Water Molecules in Protein-Membrane Simulations?

I have protein-membrane simulations (PDB, PSF, DCD) and have noticed that water molecules near the protein are not visible in the simulations. How can I fix this issue? Is there a way to place the...

04 August 2024 1,200 2 View

Does long-term culture of murine Monocytes result in macrophage differentiation?

Hi, I am isolating monocytes from the bone marrow using the Mouse Monocyte EasySep kit. I want to treat these cells and monitor expression of specific markers over the course of 10 days. I will...

04 August 2024 7,282 2 View

To perform transfection with DharmaFECT Duo in AGS cells. Could you tell me what the ideal concentration is to avoid significant cytotoxicity?

I would like to perform transfection with the reagent DharmaFECT Duo (Horizon) on the AGS cell line. Could you please inform me of the optimal concentration to use without causing cytotoxicity in...

03 August 2024 3,851 1 View

Can i quantify a nanoparticle encapsulated in cell culture medium by hplc?

Hello, if you made a transwell assay where you incubate the cells with a nanoparticle-encapsulated drug and considering that in the oposite compartment you'll have both the free and encapsulte...

03 August 2024 2,730 1 View