To the question above, I know there is a RoB issue AFTER, but not sure if there is before. Another question...can per-protocol analyses be enough (for masters level dissertation) to cover RoB regardless of dropout or not? I really can't get my head around the difference in RoB analyses (per-protocol and intention-to-treat) on my papers, seems to be the same answer for everything. My tutor told me that per-protocol analyses is fine for all my studies, but I wanted to check this...I'm currently writing a Cochrane-style systematic review and meta analysis.
Thanks for your support :)
I think there's no risk of bias concerns if participants drop out before randomization as long as more participants are recruited to cover for the drop out.
Best wishes, Victor.
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