Can any one send articles about the histopathological (toxicity ) effects of Sodium Thiosulphate in freshwater fish.
Hello Shahbaa Khalil
Sodium thiosulfate can be used as a de-chlorination agent for aquariums. Sodium thiosulfate reacts with the chlorine in chlorinated water by neutralizing it, thus, making the water safe. Standard tap water usually has a chlorine content of around 3-4 ppm chlorine, this level can be toxic to pond or aquarium fish, so treatment of tap water is always essential before replacing pond or aquarium water.
If you use 100% sodium thiosulphate, the fish will die. However, the concentration of sodium thiosulphate in water at which it will become toxic to the fish is very high. Dosage rates vary with the pH of the water, but rates between 1.6 to 2.6 parts sodium thiosulphate per one part chlorine should be adequate (excess levels of sodium thiosulphate up to 100 ppm will not harm the fish).
You may refer to the article attached below for more information on sodium thiosulfate.
https://www.groundwatergovernance.org/sodium-thiosulfate-the-best-way-to-remove-chlorine-from-your-aquarium/
Best.
Sodium thiosulfate is normally very non-toxic in low concentrations (< 1 mM). It should be easy to remove it from solution in a safe manner, and I would not expect it to persist long in a fish tank. If you add a slight molar excess of sodium thiosulfate compared to the chlorine levels in tap water (~ 0.5 mM), they should mutually titrate each other, so I can't see you having any major problems.
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